Caroline J. Smith

Position: 
Assistant Professor
No
Degree: 
Ph.D. - Thermal Physiology, Loughborough University, UK
Office: 
Convocation Center 052
Phone: 
828-265-8652
Fax: 
828-262-3138

Education

  • Postdoctoral Research Fellow, The Pennsylvania State University (2010-2013)
  • Specialization: Thermal and microvascular physiology
  • Ph.D. Loughborough University, UK (2005-2009)
  • Specialization; Thermal Physiology
  • B.Sc. (Hons) Human Biology, Loughborough University, UK (2002-2005)

Current Teaching

  • ES 3005: Physiological Assessment
  • ES 2032: Anatomy & Physiology II

Professional Affiliations

  • American Physiological Society
  • American College of Sports Medicine

Research Interests

  • Examining in vivo and in vitro signaling mechanisms underlying thermoregulatory and microvascular dysfunction in diabetic and cardiovascular disease populations, and the impact of exercise and thermal interventions on vascular responses. Current research studies include examining changes in eccrine sweating and vascular function with heat therapy in hyperglycemic and diabetic patients, and elucidating the mechanisms by which metformin improves vascular function in type II diabetes mellitus.

Research Publications

  • Original Scientific Research Publications
  • Smith, C.J., Alexander, L.M., and W.L. Kenney. (2013). Non-Uniform, Age-Related Decrements in Regional Sweating and Skin Blood Flow. Am J Physiol Regul Integr Comp Physiol. 305(8):R877-R88
  • Smith, C.J., Santhanam, L., and L.M. Alexander. (2013). Rho-Kinase activity and cutaneous vasoconstriction is upregulated in essential hypertensive humans. Microvasc Res.87:58-64
  • Smith, C.J., Kenney, W.L., and L.M. Alexander. (2013). Regional relation between skin blood flow and sweating to passive heating and local administration of acetylcholine in young, healthy humans. Am J Physiol Regul Integr Comp Physiol. 304:R566-R573
  • Smith, C.J., Machado-Moreira, C.A., Plant, G., Hodder, S., Havenith, G. and N.A.S. Taylor. (2012). Design Data for Footwear - Sweating Distribution on the Human Foot. Int. J. Clothing Science and Technology. 25(1):43-58.
  • Smith, C.J. and G. Havenith. (2012). Body Mapping of Sweating Patterns in Athletes: A Sex Comparison. Med Sci Sports Exerc. 44(12):2350-2361
  • Bruning, R.S., Santhanam, L., Stanhewicz, A.E., Smith, C. J., Berkowitz, D.E., Kenney W.L., and L.A. Holowatz. (2012). Endothelial nitric oxide synthase mediates cutaneous vasodilation during local heating and is attenuated in middle-aged human skin. J Appl Physiol. 112:2019-2026
  • Stanhewicz, A.E., Bruning, R.S., Smith, C.J., Kenney, W.L., and L.A. Holowatz. (2012). Local tetrahydrobiopterin administration augments reflex cutaneous vasodilation through nitric oxide-dependent mechanisms in aged human skin. J Appl Physiol. 112: 791-797
  • Smith, C.J., Santhanam, L., Bruning, R.S., Stanhewicz, A.E., Berkowitz, D.E., and L.A. Holowatz. (2011). Upregulation of iNOS contributes to attenuated eNOS-dependent cutaneous vasodilation in essential hypertensive humans. Hypertension. 58:935-942
  • Smith, C.J., and G. Havenith. (2011). Body mapping of sweating patterns in male athletes in mild exercise induced hyperthermia. Eur J Appl Physiol. 111(7):1391-1404
  • Havenith, G., Fogarty, A., Bartlett, B., Smith, C.J., and V. Ventenat. (2008). Male and female upper body sweat distribution during running measured with technical absorbents. Eur J Appl Physiol. 104:245-255